Bioequivalence of a New Generic Formulation of Erlotinib Hydrochloride 150 mg Tablets versus Tarceva in Healthy Volunteers under Fasting Conditions
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Bioequivalence Study of Donepezil Hydrochloride Tablets in Healthy Male Volunteers
The objective of this study was to investigate the bioequivalence of two formulations of 5 mg donepezil HCL tablets: Tonizep as the test and Aricept as the reference. The two products were administered as a single oral dose according to a randomized two-phase crossover with a 3-week washout period in 20 healthy Thai Male volunteers. After drug administration, serial blood samples were collected...
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PURPOSE The aim of this study was to evaluate the bioequivalence of a generic product 70 mg alendronate sodium tablets with the reference product Fosamax® 70 mg tablet. MATERIALS AND METHODS A single-center, open-label, randomized, three-period, three-sequence, reference-replicated crossover study was performed in 36 healthy Chinese male volunteers under fasting conditions. In each study peri...
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*Corresponding author E mail: [email protected] J. Pharm. BioSci. 2(2014) 44-49 Abstract This study was to compare the bioavailability and pharmacokinetic properties of test product of Metformin hydrochloride extended release formulation of 1000 mg tablet with reference product of Metformin Hydrochloride (Glucophage®) extended release formulation of 1000 mg in Indian healthy male vo...
متن کاملTwo-way Crossover Bioequivalence Study of Rosuvastatin Tablets 5 Mg in Healthy, Adult, Asian-indian Male Volunteers under Fasting Condition
Objective: To compare the bioavailability and characterize the pharmacokinetic profile of the test and reference formulations of rosuvastatin tablets 5 mg in healthy, adult, Asian-Indian male volunteers under fasting condition. Methods: An open label, randomized, two-treatment, two-period, two-sequence, single dose, two-way crossover study was conducted in forty healthy adult volunteers. All th...
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Glimepiride/metformin(2/500mg) is an oral antihyperglycemic agent for the treatment of type 2 diabetes. A generic glimepiride/metformin(2/500mg) fixed-dose combination(FDC) tablet was developed recently. This study was designed to collect data for submission to Korean regulatory authorities to allow the marketing of the test formulation. We evaluated the comparative bioavailability and tolerabi...
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ژورنال
عنوان ژورنال: Journal of Bioequivalence & Bioavailability
سال: 2014
ISSN: 0975-0851
DOI: 10.4172/jbb.1000190